(2E)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)acrylaMide - Names and Identifiers
Name | (2E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide
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Synonyms | Coumaryldopamine N-CouMaroyldopaMine trans-4-couMaroyldopaMine N-(3,4-dihydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide (E)-N-(3,4-DIHYDROXYPHENETHYL)-3-(5-HYDROXYPHENYL)ACRYLAMIDE (E)-N-(3,4-Dihydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide (2E)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)acrylaMide (2E)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)acrylamide (e)-n-(2-(3,4-dihydroxyphenyl)ethyl)-3-(4-hydroxyphenyl)-2-propenaMide (E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide (2E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide
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CAS | 103188-46-1
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InChI | InChI=1/C17H17NO4/c19-14-5-1-12(2-6-14)4-8-17(22)18-10-9-13-3-7-15(20)16(21)11-13/h1-8,11,19-21H,9-10H2,(H,18,22)/b8-4+ |
(2E)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)acrylaMide - Physico-chemical Properties
Molecular Formula | C17H17NO4
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Molar Mass | 299.32 |
Density | 1.381 |
Boling Point | 636.8±55.0 °C(Predicted) |
Flash Point | 338.928°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 9.77±0.26(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.68 |
(2E)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)acrylaMide - Introduction
N-coumenoyl dopamine is a chemical compound with the formula C10H11NO2. It belongs to the dopamine class of compounds and has similar structure and properties to dopamine.
N-coumenyl dopamine is a solid powder, white or light yellow in color, soluble in water and ethanol. It has the property of being soluble in organic solvents and acidic media. N-coumoyl dopamine has poor stability to air and light and is easily oxidized.
N-coumaroyl dopamine has a wide range of applications in the field of medicine. It is used as a dopamine receptor agonist in the treatment of Parkinson's disease and other related neurological disorders. It can increase the concentration of dopamine in the brain to improve the condition.
The preparation method of N-coumaroyldopamine is usually obtained by esterification of dopamine with coumaric acid or its anhydride. The reaction is generally carried out under acidic conditions, and commonly used catalysts include sulfuric acid.
About the safety information of N-coumenoyl dopamine, it can cause irritation of eyes, skin and respiratory system, so it is necessary to pay attention to protective measures when using it, such as wearing protective glasses, gloves and masks. In addition, for the contact of the substance, should promptly rinse with plenty of water, and seek medical help. During storage and handling, it should be kept away from fire and oxidizing agents, and stored in a dry and well-ventilated place.
Last Update:2024-04-09 19:05:44